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COVID-19 related multisystem inflammatory syndrome in children (MIS-C): a case series from a tertiary care hospital in Sri Lanka

Authors:

Maheshika Jayasinghe ,

Colombo North Teaching Hospital, Colombo, LK
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Manel Panapitiya

Colombo North Teaching Hospital, Colombo, LK
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Abstract

Although it has clinical features that overlap with Kawasaki disease (KD) and toxic shock syndrome (TSS), an intense inflammatory storm distinguishes MIS-C. We report four children with laboratory evidence of Severe Acute Respiratory Syndrome - coronavirus - 2 (SARS-CoV-2) infection presented with persistent fever, mucocutaneous signs, and raised inflammatory markers associated with remarkable multi-organ involvement, particularly that of the gastrointestinal and cardiovascular systems. All of them responded well to immunosuppressive therapy, including intravenous immunoglobulin and methylprednisolone. The distinguishing clinical characteristics found in MIS-C include the age of the child, gastrointestinal symptoms, and hypotension without coronary involvement. Immediate medical care is needed for a better outcome, and most children need management in an intensive care unit.

How to Cite: Jayasinghe, M. and Panapitiya, M., 2022. COVID-19 related multisystem inflammatory syndrome in children (MIS-C): a case series from a tertiary care hospital in Sri Lanka. Anuradhapura Medical Journal, 16(2), pp.37–40. DOI: http://doi.org/10.4038/amj.v16i2.7714
Published on 15 Jul 2022.
Peer Reviewed

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