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Case Reports

Steroid-responsive encephalopathy associated with autoimmune thyroiditis presenting as major depression

Authors:

Lakshika Liyanage ,

University of Colombo, LK
About Lakshika
Postgraduate Institute of Medicine
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Charith Perera

University of Colombo, LK
About Charith
Postgraduate Institute of Medicine
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Abstract

Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT), is a rare condition that is often overlooked due to its variable clinical presentation with neuropsychiatric symptoms. However, presentation with exclusive psychiatric symptoms is rare.

 

Here we describe a case of 53-year-old female who presented with major depression and later developed overt hyperthyroidism with positive anti-Thyroid Peroxidase and anti -Thyroglobulin antibodies. With clinical suspicion of SREAT, she was started on steroid therapy which resulted in a remarkable recovery.

 

It is important to be aware of this possible association between depression and SREAT since in the majority, accurate diagnosis and treatment can produce an excellent outcome.

How to Cite: Liyanage, L. and Perera, C., 2023. Steroid-responsive encephalopathy associated with autoimmune thyroiditis presenting as major depression. Anuradhapura Medical Journal, 17(1), pp.78–81. DOI: http://doi.org/10.4038/amj.v17i1.7743
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Published on 01 May 2023.
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