Case Reports
Toxoplasma causing persistent massive cervical lymphadenopathy in a healthy young male
Authors:
Fathima Nasim ,
National hospital Kandy, Kandy, LK
Fasrina Zawahir,
National hospital Kandy, Kandy, LK
Sunil Bowattage,
National hospital Kandy, Kandy, LK
Kierthi Kularathna,
National hospital Kandy, Kandy, LK
Sachinthana Sumanasekara
National hospital Kandy, Kandy, LK
Abstract
Toxoplasma, an obligate intracellular pathogen is known to cause fatal infections in the immune-compromised host. Persistent lymphadenopathy is uncommon and may mimic viral lymphadenitis and chronic infections such as tuberculosis or hematological malignancy.
We report a case of a 22 year old student who presented with massive posterior cervical lymphadenopathy. He gave a history of close contact with cats. There were no constitutional symptoms and viral serology for CMV, EBV and HIV came negative although biochemistry and blood picture were compatible with viral infection. A diagnosis of toxoplasmosis was made with positive serology (IgM) and compatible histology showing epithelioid histiocytes forming microgranuloma with preserved lymph node architecture after excluding other etiologies. Initially a conservative approach was adapted but due to non-resolution of lymphadenopathy co- trimoxazole was initiated with a positive response.
How to Cite:
Nasim, F., Zawahir, F., Bowattage, S., Kularathna, K. and Sumanasekara, S., 2023. Toxoplasma causing persistent massive cervical lymphadenopathy in a healthy young male. Anuradhapura Medical Journal, 17(1), pp.82–87. DOI: http://doi.org/10.4038/amj.v17i1.7746
Published on
01 May 2023.
Peer Reviewed
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